Find out why Deflux could be a good choice for your child

Deflux may be right for your child

With an established safety and efficacy profile in VUR grades II-IV, Deflux may be an alternative to open surgery or long-term antibiotics

If your child has been diagnosed with vesicoureteral reflux (VUR), you and your doctor will need to discuss treatment options. For many parents, the prospect of open surgery for their child is terrifying. But keeping your child on antibiotics for long periods may not be the answer either.

Deflux has an established safety profile and can provide an effective option.

Deflux is an injectable sugar-based gel that can help prevent the infected urine from backing up into the kidneys. The minimally invasive procedure is done in an outpatient setting, although general anesthesia is required. Treatment with Deflux is quick and may produce immediate results—which means your child can usually return to his or her normal activities the day after the procedure.

In fact, in a survey of 91 families, 60% of parents preferred treatment with Deflux if they knew prolonged antibiotic therapy had to continue for 3-5 years or when operative treatment was required.1

In a 2018 study, 94% of patients stated satisfaction with their Deflux procedure.2

Ask your doctor if Deflux is a possible solution for your child. If it is, be sure to ask for a referral to a pediatric urologist, a specialist who will perform the Deflux procedure.

Safety and efficacy of treatment in children under one year of age have not been established. Safety and efficacy of treatment of duplex kidney systems have not been established.

Patients should not receive DEFLUX (hyaluronic acid/dextranomer) if they have any of the following conditions: kidneys that don’t work (non-functional kidney[s]), bulging or herniation in the skin of the bladder (hutch diverticulum), swelling at the bottom of the ureter (ureterocele), a disorder in eliminating urine (active voiding dysfunction), and ongoing urinary tract infection.

  1. Ogan K, Pohl HG, Carlson D, Belman AB, Rushton HG. Parental preferences in the management of vesicoureteral reflux. J Urol. 2001;166(1):240-243.
  2. Lightfoot MA, Bilgutay AN, Tollin N, et al. Long-term clinical outcomes and parental satisfaction after dextranomer/hyaluronic acid injection for primary vesicoureteral reflux. Children’s Healthcare of Atlanta. 2018 SPU Conference.