Clinical Documentation

Safety

• Snodgrass WT. Obstruction of a dysmorphic ureter following dextranomer/hyaluronic acid copolymer. J Urol 2004; 171: 395-6.
  Stenberg A, Lackgren G. A new bioimplant for the endoscopic treatment of vesicoureteral reflux: experimental and short term clinical results. J Urol 1995; 154: 800-3.
• Stenberg A, Larsson E, Lackgren G. Endoscopic treatment with dextranomer-hyaluronic acid for vesicoureteral reflux: histological findings. J Urol 2003; 169: 1109-13.
• Stenberg AM, Sundin A, Larsson BS, et al. Lack of distant migration after injection of a 125iodine labeled dextranomer based implant into the rabbit bladder. J Urol 1997; 158: 1937-41.
• Stenberg AM, Larsson E, Lindholm A, et al. Injectable dextranomer-based implant: histopathology, volume changes and DNA analysis. Scand J Urol Nephrol 1999; 33: 355-61.

Efficacy (VUR)

• Capozza N, Patricolo M, Lais A, et al. Endoscopic treatment of vesico-ureteral reflux: twelve years' experience. Urol Int 2001; 67: 228-31
• Capozza N, Caione P. Dextranomer/hyaluronic acid copolymer implantation for vesico-ureteral reflux: a randomized comparison with antibiotic prophylaxis. J Pediatr 2002; 140: 230-4.
• Capozza N, Lais A, Matarazzo E, et al. Influence of voiding dysfunction on the outcome of endoscopic treatment for vesicoureteral reflux. J Urol 2002; 168: 1695-8.
• Capozza N, Caione P. [Role of the endoscopic treatment of vesicoureteal reflux. A 16-years' experience]. Minerva Pediatr 2003; 55: 607-14.
• Capozza N, Lais A, Nappo S, et al. The role of the endoscopic treatment of vesicoureteal reflux: a 17-year experience. J Urol 2004; 172: 1626-8.
• Elmore JM, Ewalt DH, Snodgrass WT. Initial results of DEFLUX injection for vesicoureteral reflux: the Dallas experience. Presented at AUA 2003.
• Kirsch AJ, Perez-Brayfield MR, Scherz HC. Minimally invasive treatment of vesicoureteral reflux with endoscopic injection of dextranomer/hyaluronic acid copolymer: the Children's Hospitals of Atlanta experience. J Urol 2003; 170: 211-5.
• Kirsch AJ, Perez-Brayfield M, Smith EA, et al. The modified STING procedure to correct vesicoureteral reflux: improved results with submucosal implantation within the intramural ureter. J Urol 2004; 171: 2413-6.
• Lackgren G, Wahlin N, Skoldenberg E, et al. Long-term followup of children treated with dextranomer/hyaluronic acid copolymer for vesicoureteral reflux. J Urol 2001; 166: 1887-92.
• Lavelle MT, Conlin MJ, Skoog SJ. Subureteral injection of DEFLUX for correction of reflux: analysis of factors predicting success. Urology 2005; 65: 564-7.
• Oswald J, Riccabona M, Lusuardi L, et al. Prospective comparison and 1-year follow-up of a single endoscopic subureteral polydimethylsiloxane versus dextranomer/hyaluronic acid copolymer injection for treatment of vesicoureteral reflux in children. Urology 2002; 60: 894-7.
• Puri P, Chertin B, Velayudham M, et al. Treatment of vesicoureteral reflux by endoscopic injection of dextranomer/hyaluronic Acid copolymer: preliminary results. J Urol 2003; 170: 1541-4.
• Yucel S, Ucar M, Guntekin E, et al. The effect of location of the ureteric orifice on the efficacy of endoscopic injection to correct vesico-ureteric reflux. BJU Int 2005; 95: 1314-8.

Efficacy (VUR: ‘complicated’ cases)

• Lackgren G, Wahlin N, Skoldenberg E, et al. Endoscopic treatment of children with bladder dysfunction and vesicoureteral reflux with dextranomer/hyaluronic acid copolymer – long-term results. Presented at ICCS 2002.
• Lackgren G, Wahlin N, Skoldenberg E, et al. Endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid copolymer is effective in either double ureters or a small kidney. J Urol 2003; 170: 1551-5.
• Ozok U, Eroglu M, Imamoglu A, et al. Subureteral dextranomer/hyaluronic acid copolymer injection for vesicoureteral reflux in transplant candidates. J Endourol 2005; 19: 1185-7.
• Perez-Brayfield M, Kirsch AJ, Hensle TW, et al. Endoscopic treatment with dextranomer/hyaluronic acid for complex cases of vesicoureteral reflux. J Urol 2004; 172: 1614-6.

Cost-effectiveness (VUR)

• Kobelt G, Canning DA, Hensle TW, et al. The cost-effectiveness of endoscopic injection of dextranomer/hyaluronic acid copolymer for vesicoureteral reflux. J Urol 2003; 169: 1480-4; discussion 1484-5.

Clinical implications (VUR)

• Capozza N, Matarazzo E, Nappo S, et al. Treatment of vesico-ureteral reflux: a new algorithm based on parental preference. BJU Int 2003; 92: 285-8.
• Lackgren G, Wahlin N, Stenberg A. Endoscopic treatment of children with vesico-ureteric reflux. Acta Paediatr 1999; 88 (Suppl 431): 62-71.
• Lackgren G. Endoscopic treatment of vesicoureteral reflux and urinary incontinence in children. AUA Update Series 2003; Volume XXII, Lesson 37: 294-9.
• Stenberg A, Hensle TW, Lackgren G. Vesicoureteral reflux: a new treatment algorithm. Curr Urol Rep 2002; 3: 107-14.

Efficacy (incontinence)

• Caione P, Capozza N. Endoscopic treatment of urinary incontinence in pediatric patients: 2-year experience with dextranomer/hyaluronic acid copolymer. J Urol 2002; 168: 1868-71.
• Lottman HB, Margaryan M, Bernuy M, et al. The effect of endoscopic injections of dextranomer-based implants on continence and bladder capacity: a prospective study in 31 patients. J Urol 2002; 168: 1863-7.
• Misseri R, Casale AJ, Cain MP, et al. Alternative uses of dextranomer/hyaluronic acid copolymer: the efficacy of bladder neck injection for urinary incontinence. J Urol 2005; 174: 1691-3.